Surgical treatment of functional disorders in patients with abnormalities of development and position of the colon

Treatment of adult patients with congenital malformations and the provisions of the colon is important, before the end of the unresolved challenge. The reason is, first of all individuality and diversity of forms of anomalies and their clinical manifestations, and the lack of common approaches to the treatment of such patients.

Surgical treatment of chronic colonic stasis

Chronic colonic stasis is one of the urgent problems of modern medicine. This is due to the fact that none of the plurality of the proposed methods of conservative and surgical treatment does not eliminate completely the human suffering (VL Golovachov 1979; .. VD Fedorov, GI Vorobiev, 1986; PP . Romanov. 1987).The basis of our work lay a large clinical material that includes observation of 1340 patients with chronic colonic stasis, 80 of which are made specifically developed reconstructive surgery.

The role of ABC-transporter (multidrug resistance markers) in tumors and normal colon mucosa of human

Despite the undoubted success of modern cancer chemotherapy, the problem of increasing the effectiveness of cancer treatment is still topical. In addition to the high toxicity of cytostatics, which restricts adequate chemotherapy resistance of tumors is a major obstacle in achieving the desired effect of therapy.

The genetics of cancer of the gastrointestinal tract

Value problems of gastric cancer and colon cancer is not reduced over the years and is becoming more acute with increasing incidence. Although the basic etiology of these tumors remains poorly understood, but it is already known that the transformation of cells and the occurrence of gastric cancer and colon cancer are caused by dynamic changes in the cellular genome, associated with both the germinal and somatic mutations, namely to date clearly established that the development of these tumors affect the number of genetic changes, including genes located on different chromosomes.

Clinical value of ultrasonography in the diagnosis of colon cancer

Currently, in all developed countries there is a significant increase in the incidence of colon cancer, and 60 - 80% of patients with newly diagnosed defined stage III - IV disease. It is therefore important to determine the degree of preoperative invasion of the intestinal wall to reveal tumor invasion and tissue surrounding organs, metastasis to regional and distant lymph nodes (LN) and in the liver. From the receipt of such information depends largely on the amount of therapeutic tactics and surgery. In recent years, for these tasks using ultrasonography (US) [4, 8, 10].

Diagnosis and treatment of colon cancer

In recent decades, many countries around the world, including in Russia, there is an increased incidence of colon cancer (Colon Cancer). According to the Cancer Research Center, in 1960, was registered 5007 patients with newly diagnosed Colon Cancer, and by 1992 the number had more than 7 times and was 37 999. At present, the structure of the cancer incidence Colon Cancer came in third place (N.N.Trapeznikov and I.V.Poddubnaya, 1996). The incidence of malignant neoplasms of the colon and the blind men is 11.6 and for women - 9.2 per 100 thousand. Adult population.

Transanal endomicrosurgery as a method of treatment of large villous structures of the rectum

Search for treatment of epithelial tumors of the rectum, combining radical removal of the tumor on the one hand and on the other a low invasiveness, led to the development and implementation of Coloproctology transanal endomikrohirurgii (TEM). In 1983, Buess G. et. all for the first time published a report on the application of a new method of transanal removal of benign tumors of the rectum using the system for microsurgical manipulation - TEM (Transanal endoscopic microsurgery) [5].

Treatment of colon polyps and anal canal

Most of the benign tumors (polyps, villous formation) in the practice of Coloproctology occurs frequently. At this time, when modern diagnostics (sigmoidoscopy, colonoscopy, barium enema) identification of polyps do not cause difficulties. Most of the benign tumors of the colon is rarely harmful to health and does not pose a threat to life, but the main clinical and social significance of their determined by another circumstance - is likely malignant.

Comparative analysis of cardiac activity on the stages of surgical treatment in patients with rectal cancer

Along with the improvement of operative, anesthetic technique, the success of surgical treatment often directly determined by a complex comorbidity, state of the cardiovascular system, its spare capacity. Special attention in this regard deserves complex pathological effects experienced by the myocardium and the entire cardiovascular system as a whole against the background of the development of cancer, particularly in the rectal area.

Repeated surgery in complicated and locally advanced colorectal cancer

In almost all developed countries continues to increase the incidence of colorectal cancer [6]. Despite some advances in the diagnosis of colorectal cancer still remains a high percentage of patients with complicated and running over the disease [3, 6, 10]. The main and most effective form of treatment for colon cancer is surgery [1,4, 9]. According to specialized clinics onkoproktologicheskih resectability rate this localization is quite high and is 68-82%, whereas in the surgical wards of general health services, this figure is lower - less than 50% [5, 7].

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